Rheumatoid Arthritis (RA) Panel with Reflex to Rheumatoid Factors, IgA, IgG, and IgM by ELISA
Ordering Recommendation
Aids in the workup of suspected rheumatoid arthritis or undifferentiated inflammatory arthritides. If anticyclic citrullinated peptide (anti-CCP) IgG or rheumatoid factor is positive, rheumatoid factors IgA, IgG, and IgM will be performed to aid in prognosis. The preferred test for initial workup is Rheumatoid Arthritis (RA) Panel (3016634).
New York DOH Approval Status
Specimen Required
Fasting specimen preferred.
Serum separator tube (SST).
Allow serum to clot completely at room temperature before centrifuging. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.8 mL) Serum is the only acceptable specimen type for this test without a disclaimer.
Refrigerated.
Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.
After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month (should not be thawed more than once)
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)/Quantitative Immunoturbidimetry
Performed
Sun-Sat
Reported
1-4 days
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Rheumatoid Factor | 0-14 IU/mL | |
Carbamylated Protein Antibody, IgG | 0-19 Units | |
Cyclic Citrullinated Peptide Ab, IgG/A | 19 Units or less |
Interpretive Data
Refer to report.
Analyte Specific Reagent (ASR)
Note
If CCP IgG/IGA is 20 units or greater and/or rheumatoid factor is 15 IU/mL or greater, then Rheumatoid Factor, IgA, IgM, and IgM by EIA will be performed. Additional charges apply.
Hotline History
Hotline History
CPT Codes
86200; 86431; 83516 if reflexed, add 83516 x3
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050465 | Rheumatoid Factor | 11572-5 |
3003993 | Carbamylated Protein Antibody, IgG | |
3016633 | Cyclic Citrullinated Peptide Ab, IgG/A | 57093-7 |
Aliases
- Carbamylated Protein IgG
- CarP IgG
- CCP and RF IgA IgG IgM
- CCP, RF, RF isotypes
- RA
- RA panel reflex RF
- RF